Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Aug 7;203(8):1883–1889. doi: 10.1084/jem.20060336

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2006, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 1. — Altered JNK and p38 MAPK signaling in DUSP1^−/− BMMs. (A) 10⁶ DUSP1^+/+ or DUSP1^−/− BMMs were pretreated with vehicle or 100 nM Dex for 4 h and stimulated with LPS for the indicated times. Lysates were blotted for DUSP1 or tubulin-α (top) and total or phosphorylated MAPKs (bottom). Two exposures of the same DUSP1 Western blot are shown to illustrate differences in basal and LPS-induced DUSP1 protein expression. (B) DUSP1^+/+ or DUSP1^−/− BMMs were pretreated with 1 nM to 1 μM Dex for 4 h and stimulated with LPS for 4 h. In two separate representative experiments, lysates were sequentially blotted for DUSP1 and tubulin-α (top) or for phosphorylated and total MAPKs (bottom). (C) Wild-type and GR^dim BMMs were pretreated with 1 nM to 1 μM Dex for 4 h and stimulated with LPS for 4 h. Lysates were blotted for DUSP1 or actin.