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. 2006 Aug 7;203(8):1963–1975. doi: 10.1084/jem.20060039

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Copyright © 2006, The Rockefeller University Press

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Figure 1. — Localization of LCMV in the brain of a carrier mouse persistently infected from birth. (A) Six-μm sagittal brain sections from C57BL/6 LCMV carrier mice (n = 3) at >8 wk of age were stained with a polyclonal anti-LCMV antibody (green) and a nuclear dye (red). Brain reconstructions were performed to illustrate the anatomical distribution of LCMV. Note the equal distribution of LCMV throughout the brain parenchyma. (B) High resolution analyses of LCMV-infected cells (green; C and D) in the brain parenchyma confirmed that >99% of the cells colocalized with neuronal staining (red; B and D). Overlapping fluorescence appears in D.