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. 2006 Sep 4;203(9):2109–2119. doi: 10.1084/jem.20052267

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Copyright © 2006, The Rockefeller University Press

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Figure 2. — CO protects against and reverses chronic hypoxia-induced experimental PAH in rats. (A–C) CO reverses pathology associated with chronic hypoxia-induced PAH, including restoring body weights (A) and lowering hypoxia-induced increases in mPAP (B), as well as RV/LV + IVS ratios (C). Results represent means ± SD of six rats/group. *, P < 0.01 versus CO/hypoxia- and air-treated controls.