Table II.

MAPC contribution to hematopoietic stem and progenitor populations in secondary recipients

Source of primary BM
Population	KTLS	MAPCs
LT-HSC	69.6 ± 12%	64.6 ± 27%
CLP	56.9 ± 9%	57.4 ± 18%
CMP	63.5 ± 21%	37.4 ± 27%
GMP	64.3 ± 22%	38.9 ± 30%
MEP	62.5 ± 21%	36.4 ± 27%

0.75 × 10⁶ eGFP MAPCs were transplanted into lethally irradiated NOD-SCID mice with 2 × 10⁵ Sca-1–depleted cells of host origin. 20 wk after transplant, 10⁶ BM cells were serially transplanted into lethally irradiated C57BL-CD45.1⁺ hosts. At week 24, BM was harvested and assessed for primary donor (eGFP⁺CD45.2⁺) contribution to LT-HSCs (KLSFlk2⁻CD34⁻), common lymphoid progenitors (CLP; Lin⁻ckit^lowSca-1^lowIL7Rα⁺Flk2⁺), common myeloid progenitors (CMP; Lin⁻ckit⁺ Sca-1⁻CD16/32^lowCD34⁺), granulocyte macrophage progenitors (GMP; Lin⁻ckit⁺Sca-1⁻CD16/32⁺CD34⁺), and megakaryocyte erythrocyte progenitors (MEP; Lin⁻ckit⁺Sca-1⁻CD16/32^lowCD34⁻). Data for n ≥ 3 mice per group is shown.