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. 2007 Oct 1;204(10):2407–2422. doi: 10.1084/jem.20070628

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Copyright © 2007, The Rockefeller University Press

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Figure 4. — Multiple cytokine secretion in IRAK-4–deficient PBMCs. PBMCs from three healthy controls and three IRAK-4–deficient patients (P17, 18, and 22) were activated with various TLR agonists for 24 h. Cytokine levels are represented as ratios of the mean secretion observed in the three IRAK-4–deficient patients to that in three healthy controls. Cytokines represented in gray are not induced upon the stimulation of control PBMCs.