Skip to main content
. 2007 Oct 29;204(11):2553–2559. doi: 10.1084/jem.20070254

Table I.

Binding of threshold ligands to thymocytes from three different TCR transgenic mouse strains (T1, S14, and OT-1 TCR)

TCR /ligand pMHC monomers
pMHC tetramers
DP thymocytes
(K d [M])
SP thymocytes
(K d [M])
SP thymocytes
(r 1/2 [M])
T1/4A-Kd 5.4 ± 1.6 × 10−6 5.5 ± 1.8 × 10−6 Not done
T1/4S-Kd 6.1 ± 1.1 × 10−6 7.9 ± 2.0 × 10−6 9.0 ± 1.5 × 10−8
S14/4L-Kd 6.4 ± 1.5 × 10−6 6.2 ± 1.7 × 10−6 8.8 ± 1.6 × 10−8
OT-1/OvaT4-Kb Not done Not done 7.6 ± 0.7 × 10−8

Mean values and SEMs of at least three independent experiments are shown.