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. 2007 Nov 26;204(12):2889–2897. doi: 10.1084/jem.20071283

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Copyright © 2007, The Rockefeller University Press

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Figure 4. — Vav is required for ROS production in DCs. ROS production in BMDCs was determined with the chemiluminescent substrate lucigenin. Cells were stimulated with 5 μl/sample latex beads (A), 1 μg/ml plate-bound fibronectin (Fbn; B), 10 μg/ml LPS (C), 10 μg/ml peptidoglycan (PGN; D), and 20 μg/ml zymosan (Zym; E). (inset) Cells stimulated with 50 ng/ml PMA for 60-70 min. RLU, relative light units.