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. 2007 Apr 16;204(4):723–734. doi: 10.1084/jem.20061424

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Copyright © 2007, The Rockefeller University Press

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Figure 8. — CCR7 deficiency does not affect localization of FoxP3⁺ cells in the thymus. (A) Cryosections of 8–12-wk-old wild-type B6 (+/+) and CCR7-deficient B6 mice (−/−) were stained with antibodies as indicated. Shown are sections representative of four animals analyzed. Bars, 200 μm. (B) Thymocytes were isolated from 8–12-wk-old C57BL/6 and CCR7-deficient mice and stained with antibodies against CD4, CD8, and FoxP3. Shown are the number of CD4⁺CD8⁻FoxP3⁺ cells (mean + SD; n = 3).