Figure 4.
Placental thrombosis in FvL mice. The number of placental thrombi was similar in placentas of wild-type and ThbdProPro embryos (see Results). Thrombi were identified on serial sections by hematoxylin and eosin staining (a, c, and e), and immunostaining with antifibrinogen antibodies (b) and anti–p-selectin antibodies (d and f). e and f are enlarged views of the boxed areas in c and d. Arrows indicate clots. Bars, 0.1 mm.