Figure 7.

Quantitative analysis of muscle regeneration after circulating MO depletion. CD11b-DTR mice were treated as in Fig. 6, and in each case the number of (A) necrotic myofibers, (B) phagocyted myofibers, (C) regenerating basic myofibers, and (D) centrally nucleated regenerating myofibers was evaluated. Closed squares represent the control corresponding to Fig. 6 B; open diamonds represent simultaneous DT and notexin injections corresponding to Fig. 6 C; open triangles represent a DT injection 12 h before notexin injection corresponding to Fig. 6 D; open squares represent a double DT injection corresponding to Fig. 6 E; and closed circles represent a DT injection 4 d after notexin injection corresponding to Fig. 6 F. Results are expressed as the percentage of total counted myofibers and are the means of at least two experiments.