Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 May 14;204(5):1207–1216. doi: 10.1084/jem.20070087

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2007, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 2. — Normal Uracil incision activity in patients' cell lines. Protein extracts from control fibroblasts (control 1); control EBV B cell line (control 2); P2, P3, and P4 fibroblasts; and P1 and P5 EBV B cell lines were mixed with double-stranded fluorescein-labeled oligonucleotide substrate with or without a single dU/dG mismatch. Cleavage of the probe containing a dU/dG mismatch revealed an efficient base excision activity in patients and controls. No detectable base excision activity was observed with UNG^−/− cells or in the absence of protein extracts (−).