Figure 6.
Vaccinia virus–specific CD8+ T cells express intracellular granzymes and perforin. Perforin and granzyme expression on KVD tetramer-binding cells is shown as red contour plots overlayed on density plots of the total CD8+ T cell population. An APC-conjugated tetramer was used in A; a PE-conjugated tetramer was used in B. Representative staining from one of three donors.
