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. 2007 Jul 9;204(7):1653–1664. doi: 10.1084/jem.20062648

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Copyright © 2007, The Rockefeller University Press

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Figure 6. — The expression of Notch pathway components in wild-type and RBP-J–deficient DCs. The expression of Notch receptors and target genes in splenic DCs was determined by qPCR. Shown are the expression levels of the indicated genes relative to the expression in wild-type CD8⁻ DCs (indicated by the horizontal dashed line). The lack of signal above threshold is indicated by an asterisk. (left) The expression in splenic T or B lymphocytes, monocytes/macrophages (M), and CD8⁻ DCs from wild-type mice. (right) The expression in CD8⁻ and CD8⁺ DCs from control (RBP-J^fl/fl) and CKO (RBP-J^fl/fl CD11c-Cre⁺) mice. Results represent mean relative values ± SD of triplicate qPCR reactions. ND, not determined.