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. 2007 Aug 6;204(8):1999–2008. doi: 10.1084/jem.20070304

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Copyright © 2007, The Rockefeller University Press

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Figure 2. — Fibrinogen accumulates through the damaged neurovasculature. (A) Fibrin deposition parallels age-dependent Aβ accumulation. TgCRND8 cortex and hippocampus were isolated, and homogenates were assayed each for fibrinogen and Aβ_1-40 by ELISA. Each point represents one TgCRND8 mouse. Correlation coefficients are indicated. (B) The same cortex and hippocampus homogenates were assayed each for fibrinogen and Aβ_1-42 by ELISA.