Table 2.

Comparison of experimental data and theoretical predictions for the effect of exogenous extracellular macromolecules (dextrans) on the tortuosity factor λ

Prefusate medium	Experimental data*	Bayesian approximation, (Eq. 10)		Stokes–Einstein prediction, (Eq. 6)
	λ	φ/α	λ	η, mPas	λ
ACSF	1.57	0.22	(1.57)	1.05	(1.57)
+1% 70 kDa	1.75	0.38	1.70	1.47	1.85
+2% 70 kDa	1.72	0.54	1.83	1.70	2.00
+2% 40 kDa	1.77	0.54	1.83	1.47	1.85

*Data from Prokopová et al (34): Left column, artificial cerebro-spinal fluid (ACSF) with various concentrations of 40 or 70 kDa dextran; φ/α, volume fraction of large molecules (including dextrans) in the extracellular space; η, viscosity of perfusate measured in mPas.