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. 2007 Sep 3;204(9):2023–2030. doi: 10.1084/jem.20070064

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Copyright © 2007, The Rockefeller University Press

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Figure 5. — Intravenously administered anti–MHC class I antibody does not affect proliferation of brain-infiltrating CD8 T cells in this model of antigen-specific CD8 T cell traffic. (A) Merged confocal micrograph after double immunofluorescence for CD8 (red) and Ki67 (green) on striatum from CL4 mice 3 d after HA injection. (B) Ki67 index of brain-infiltrating CD8 T cells at several time points after intrastriatal HA injection in CL4 mice. (C) Ki67 index of brain-infiltrating CD8 T cells 3 d after intrastriatal HA injection (day 0) in CL4 mice receiving i.v. blocking anti–MHC class I antibody or control IgG on day 2 (two-tailed Student's t test, P = 0.844). Bar, 20 μm.