Table II.

EC₅₀ values for alanine point-mutant mouse chimeric TLR5 molecules stimulated with wild-type and mutant flagellins

^aSchematic of alanine point-mutant mouse TLR5 molecules.

^bEC₅₀ values and standard deviations are listed in ng/ml, and values were calculated from at least three independent experiments, each run in duplicate.

^cEC₅₀ values for each TLR5 construct were compared to parental TLR5, and p-values were calculated using a two-tailed Student's t test. p-values >0.05 are not shown.