Figure 7.

Hyperphosphorylation of τ at 3 hr after heat shock is caused by increased phosphorylation of pre-existing τ. Data values shown in Tables 1 and 2 from all six gonadectomized groups at each time point after heat shock and non-heat-shocked controls were combined. Note the constant amounts of total τ, and the statistically significant increase and decrease in nonphosphorylated τ at 0 and 3 hr after heat shock, respectively. The values of P shown are based on comparison with the control values.