Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 Aug;26(3):704–716. doi: 10.1111/j.1460-9568.2007.05684.x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

The Authors (2007). Journal Compilation Federation of European Neuroscience Societies and Blackwell Publishing Ltd

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

PMC Copyright notice

Fig. 1 — The sharp wave/ripple (SWR) onset times of different cells is opposite to their order before SWRs. (A)Representative example illustrating the spike-time regression procedure. Traces at the top show wide-band (1 Hz−5 kHz) recorded channels from three different CA1 sites (three different tetrodes) and the band-pass filtered (150–250 Hz) trace of the third channel, in which the SWR event is clearly present. A 200 ms SWR window was centred at the SWR peak time and is marked by the horizontal line above the top trace. The first and last spike-times are marked by bold raster lines on the raster plot and arrows mark their spike-time intervals. The time axis on the bottom illustrates spike-times relative to the leading border of the SWR. (B)Regression analyses of the times of last spikes before and first spikes during exploration-associated (e)SWRs all produced negative correlations for different sessions, but not during immobility-associated (i)SWRs or SWR that occurred at least 15 s outside of exploratory periods (iSWR-15 s). The frequency histograms of regression coefficients measured in different recording sessions are shown. Grey bars show those recording sessions with significant (P < 0.05) regressions, with the remaining sessions indicated in white. Spike-times of different cells measured during different SWRs were analysed together. Negative spike-times before SWR onset are relative to the leading SWR border for eSWRs (as shown in A) or relative to the end-time of the previous exploration sessions for iSWRs. (C)Average (± SEM) of correlation coefficients of last pre-SWR and first SWR spike-times. (eSWR: n = 26; iSWR: n = 26; iSWR-15 s: n = 24 sessions).