Table 1.
Genome-wide association scan | Platform | Cases (n) | Control subjects (n) | Population | T2D phenotype |
---|---|---|---|---|---|
Sladek et al. [5] | Illumina HumanHap300 Infinium Human1 | 661 | 614 | France | Family history of T2D, AAO < 45 years, BMI < 30 kg/m2 |
WTCCC [1] | Affymetrix 500k | 1924 | 2938 | UK | Partial enrichment for family history ofT2D, AAO < 65 years |
Scott et al. [4] | Illumina HumanHap300 | 1161 | 1174 | Finland | Partial enrichment for family history |
DGI [3] | Affymetrix 500k | 1464 | 1467 | Finland, Sweden | Partial enrichment for family history |
Steinthorsdottir et al. [6] | Illumina HumanHap300 | 1399 | 5275 | Iceland | No specific enrichment for family history, young AAO or BMI |
AAO, age at onset; BMI, body mass index; DGI, Diabetes Genetics Initiative; T2D, Type 2 diabetes; WTCCC, Wellcome Trust Case Control Consortium.