Table 2.
Oxford series | London series | |||
---|---|---|---|---|
Controls | Patients | Controls | Patients | |
DAO | (n = 6–9) | (n = 7–8) | (n = 6–7) | (n = 6) |
mRNA | ||||
CB | 7.65 ± 1.11 | 9.69 ± 1.43 | 11.74 ± 0.86 | 15.97 ± 1.29 |
DPFC | 8.70 ± 2.77 | 6.99 ± 0.90 | 4.335 ± 2.52 | 9.38 ± 3.69 |
Protein | ||||
CB | 0.53 ± 0.06 | 0.60 ± 0.08 | 1.96 ± 0.44 | 3.40 ± 0.47 |
DPFC | n.d. | n.d. | n.d. | n.d. |
SRR | (n = 6–8) | (n = 6–10) | (n = 7–9) | (n = 6–9) |
mRNA | ||||
CB | 1.18 ± 0.33 | 1.02 ± 0.21 | 1.10 ± 0.16 | 0.89 ± 0.15 |
DPFC | 1.02 ± 0.13 | 0.71 ± 0.17 | 0.95 ± 0.16 | 1.27 ± 0.10 |
Protein | ||||
CB | 0.63 ± 0.08 | 0.70 ± 0.09 | 0.79 ± 0.05 | 0.66 ± 0.07 |
DPFC | 0.68 ± 0.08 | 0.88 ± 0.06 | 0.48 ± 0.06 | 0.59 ± 0.07 |
Values are means ± SEM. mRNA normalized to r18s; protein normalized to cyclophilin. n.d., not determined.