Tumor-burdened lymph nodes and uninvolved lymph nodes, stratified by metastatic status and level, were examined for the presence of DC-LAMP+ (4a), CD123+ (4b) and Langerin+ (4c) dendritic cells. Closed and open symbols represent lymph nodes in metastatic and nonmetastatic patients, respectively. For CD123, mean differences between metastatic and nonmetastatic patients were not significant, due to large interpatient variation yet low intrapatient variation in the nonmetastatic patients (4d). Lymph nodes from individual patients are labeled by patient identification number.