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Hybrid-ITR vector genomes enhance directional heterodimerization after infection of C57BL/6 Rag1-KO mouse heart. Directional genome heterodimerization was assessed in the heart after tail vein injection of the indicated viral combinations in the presence of Doxil. β-Galactosidase enzymatic assays on tissue lysates 2 weeks postinfection are given. Data represent mean (±SEM) β-galactosidase activity of two to five independent infections for each group as indicated.
