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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Mol Immunol. 2007 Aug 20;45(1):204–217. doi: 10.1016/j.molimm.2007.04.023

Fig. 7.

Fig. 7

Effect of all-trans-retinoic acid, IFN-γ, and LPS on hCAP18 promoter activity. (a) A549 cells were transiently transfected with pGL3-1739/-74 construct, then stimulated with IFN-γ and/or LPS. Luciferase activity was measured after 18h. Stimulation with either IFN-γ or LPS alone decreased promoter activity. An additive repressive effect was noted using IFN-γ and LPS simultaneously. (b) U937 and K562 cells were transiently transfected with the indicated 5′ deletion promoter constructs. ATRA were added and luciferase activity was determined 18h after transfection. ATRA induces hCAP18 promoter in U937 cells but not in K562 cells.