Table 2.
Male-Female differentially expressed genes.
Probe Set | GenBank | Name | Gene | Chromosome | Function | a9 M/F | a47 M/F | RMA_Log2 | RMA_Log2 | Sybr-PCR |
Genes identified in both brain areas. | ||||||||||
FC | M/F FC | |||||||||
201909_ | BC010286 | ribosomal protein S4, Y-linked | RPS4Y | Yp11.3 | protein biosynthesis | 8.9 | 10.8 | 2.42E-14 | 7.67E-11 | >1700 |
204409_s_ | BC005248 | eukaryotic translation initiation factor 1A | EIF1AY | Yq11.2 | translation initiation | 1.9 | 2.3 | <1E-16 | 9.77E-13 | >72 |
204410_ | AF000987 | eukaryotic translation initiation factor 1A | EIF1AY | Yq11.2 | translation initiation | 1.6 | 1.7 | 4.09E-06 | 1.84E-09 | >72 |
205000_ | AF000984 | DEAD/H (Asp-Glu-Ala-Asp/His)box | DBY | Yq11 | RNA helicase | 6.4 | 8.5 | <1E-16 | <1E-16 | >96000 |
205001_s_ | AF000985 | DEAD/H (Asp-Glu-Ala-Asp/His)box | DBY | Yq11 | RNA helicase | 1.9 | 1.9 | <1E-16 | 5.51E-07 | >96000 |
206624_ | Y13618 | ubiquitin specific protease 9 | USP9Y | Yq11.2 | deubiquitylation | 4.7 | 5.1 | <1E-16 | <1E-16 | |
206700_s_ | U52191 | SMC (mouse) homolog | SMCY | Yq11 | transcription factor | 2.9 | 3.3 | 1.70E-07 | 6.48E-10 | >5000 |
207063_ | AF119903 | hypothetical protein PRO2834 | Yq11.2 | unknown | 1.3 | 1.5 | 4.17E-06 | 5.77E-10 | ||
207246_ | M30607 | zinc finger protein | ZFY | Yp11.3 | transcription regulation | 1.3 | 1.2 | 4.67E-08 | 8.57E-06 | |
214983_ | AL080135 | hypothetical protein DFKZp434I143 | Y | unknown | 1.9 | 2.1 | 6.13E-08 | 9.60E-08 | >100,000 | |
207703_ | AB023168 | KIAA0951 protein | Xp22.3 | unknown | 2.5 | 2.7 | 2.25E-08 | 6.97E-07 | ||
214218_s_ | AV699347 | XIST | XIST | Xq13.2 | X-gene inactivation | -6.4 | -7.8 | 1.32E-07 | 4.23E-10 | <-3400 |
221728_x_ | AK025198 | XIST | XIST | Xq13.2 | X-gene inactivation | -12 | -15 | 1.70E-08 | 4.49E-09 | <-3400 |
Selected genes identified in BA9 or BA47 only. | ||||||||||
FC | ||||||||||
211149_ | AF000994 | ubiquitously transcribed tetratricopeptide rep | UTY | Yq11 | protein-protein interaction | 1.1 | 1.2 | 0.0148 | 8.35E-07 | >67,000 |
210292_s_ | AF332218 | protocadherin 11 X-linked | PCDH11X | Xq21.3 | cell-cell recognition | 1.5 | 1.8 | 0.0012 | 1.30E-08 | |
211937_ | NM_001417 | eukaryotic translation initiation factor 4B | EIF4B | 12q12 | translation regulation | 1.2 | 1.1 | 1.21E-05 | 0.0916 | |
219737_s_ | AI524125 | protocadherin 9 | PCDH9 | 13q | cell-cell recognition | 1.3 | 1.0 | 2.77E-05 | 0.4902 |
Bold denotes p-values that passed the Benjamini-Hochberg false discovery rate screen. M/F FC, male versus female fold change (see Methods); Sybr-PCR, real-time PCR.