Table 1.

Effect of bafilomycin A₁ on short circuit current (SCC) and potential difference (PD) in the isolated rabbit/ciliary body

Bafilomycin	Bafilomycin added to aqueous side		Bafilomycin added to blood side
	SCC, μA	PD, mV	SCC, μA	PD, mV
None	−8.1 ± 0.8	0.55	−8.5 ± 0.6	0.45
1 nM	−7.7 ± 1.3	0.55	−8.5 ± 0.8	0.45
10 nM	−7.8 ± 0	0.55	−8.5 ± 0.6	0.45
100 nM	−7.7 ± 0.8	0.55	−8.5 ± 0.6	0.45
1 μM	−6.0 ± 0.9*	0.40	−10.4 ± 0.6	0.45
10 μM	−4.2 ± 0.9**	0.40	−12.4 ± 0.9*	0.40

Bafilomycin was added to the bath in increasing concentrations every 30 min and transepithelial measurements (26) were obtained. ∗, P < 0.05; ∗∗, P < 0.01.