Figure 2.

Comparison of the CRDs of FRP and other members of the FZ family. Solid black shading highlights identities present in human FRP and any other FZ family member. The consensus sequence indicates residues present in at least 8 of the 16 FZ or FZ-related proteins. ∗∗, The ten invariant cysteine residues; single asterisks indicate other invariant residues. hFRP, human FZ-related protein; hFZ (36); hFZ5 (16); mFZ3-mFZ8 (16); rFZ1 and rFZ2 (37); dFZ (21); dFZ2 (17); cFZ (16); mCOL, mouse collagen XVIII (38); hFRZB (39); and mSDF5 (40).