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(A) Toluidine blue stained semi-thin sections (×1,000) of seminiferous tubes from normal control (+/+) and Pcsk4 null mice (−/−). Arrows point at some pachytene spermatocytes (SP), round (rS) and elongated (eS) spermatids. (B) Staining for β-gal activity in the testis of wild-type (+/+) and mutant (−/−) mice. The reaction dark product is associated with testicular tubules.
