Table 3.
Parameter | Genotype
|
|
---|---|---|
+/+ | −/− | |
Velocity (μm/s) | 170 ± 18 | 170 ± 19 |
Linearity | 4.7 ± 0.1 | 5.0 ± 0.8 |
ALHmax (μm) | 8.6 ± 1.4 | 7.8 ± 0.8 |
ALHave (μm) | 7.4 ± 1.2 | 6.5 ± 0.6 |
BCF (beat/s) | 12.4 ± 0.8 | 13.1 ± 0.9 |
Circular cells | 4.5 ± 1.5 | 3.8 ± 1.2 |
HA (%) | 12.9 ± 2.1 | 6.8 ± 1.4* |
Four mice of each genotype were studied. The number of spermatozoa analyzed range from 200 to 300 per mouse. The parameters examined are defined in Materials and Methods. Values represent the mean and SD of determinations on the four mice of each genotype.
PC4 null sperm undergo hyperactivation to a significantly lesser extent (P < 0.05).