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Only CIITA-transduced sarcoma cells efficiently present exogenous intact HEL
| APC | IL-2, pg/ml
|
||
|---|---|---|---|
| Exp. 1 | Exp. 2 | Exp. 3 | |
| SaI | 0 | 0 | 0 |
| SaI/Ak | 0 | 0 | 52.8 |
| SaI/Ak/Ii-6 | 17.2 | ||
| SaI/Ak/Ii-7 | 14.5 | 0 | 0 |
| SaI/Ak/Il-9 | 0 | 0 | 0 |
| SaI/LXSN | 15 | ||
| SaI/CIITA | 376 | 171.6 | |
| TA3 | 3,696 | >1,386 | >3,234 |
APC were incubated with intact soluble HEL and 3A9 hybridoma cells, and IL-2 production was measured by ELISA. Three independent experiments are shown.
