Figure 2.

(A) Membrane conductance in response to microapplication of NMDA, but not AMPA, is increased during STP. (Upper) The upper two are responses induced by pressure ejection of NMDA at the moments indicated by downward arrowheads, (500 μM, 100 msec in duration); the lower two are responses induced by AMPA (500 μM, 100 msec in duration); before (Left) and after (Right) induction of LTP. (B) STP was expressed by whole cell EPSCs in both experimental groups. (Upper) The upper two EPSCs are obtained from the same hippocampal slice as the one shown in A for focal application of NMDA; the lower two are from that for focal application of AMPA before (Dotted) and during (Solid) STP.