Fig. 2. Histological analysis of hearts from mPDK1^+/+ and mPDK1^+/+ mice. At the indicated times the hearts were fixed in 10% formalin, embedded in wax and stained with haematoxilin and eosin. (A, D, G and J) Comparison of a representative image of heart of littermate mPDK1^–/– and mPDK1^+/+ mice of the same sex, before the fixation and staining. (B, E, H and K) Representative longitudinal sections after fixation and staining. (C, F, I and L) Representative micrographs of transversal sections of the muscular fibres. Scale bar is shown at the bottom of each set of panels.