Table I. Alignment of the five conserved motifs present in Spoll homologs.

Motifs I–V are defined Bergerat et al. (1997). DDBJ/EMBL/GenBank accession Nos for the sequences shown are: AAD52562 (H.sapiens), AAD52563 (M.musculus), P40384 (S.pombe), AAB65075 (S.cerevisiae), AADAAC61735 (D.Melanogaster), CAA92974 (C.elegans), O05208 (S.shibatae), BAA79679 (A.pernix) and O27089 (M.thermoautotrophicum). (.) denotes amino acid that is identical to C.cinereus, and the boxed amino acid (Y-94) is eaplained in text.

^aIn C.cinereus, motifs I–V encompass amino acids 85–94, 121–132, 174–189, 205–223 and 238–251, respectively.