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. Author manuscript; available in PMC: 2007 Dec 10.
Published in final edited form as: Horm Behav. 2007 Jan 27;51(4):508–515. doi: 10.1016/j.yhbeh.2007.01.006

Figure 3.

Figure 3

Both CRF1 and CRF2 receptors in the NAcc are necessary for CRF-facilitated partner preference formation in prairie voles. (A) Animals injected with 0.1 pg CRF into NAcc spent more time in contact with the partner than the stranger (p<0.01, Student’s t-test, Bonferroni level set at p<0.016). This facilitation effect was blocked by the co-infusion of a selective CRF1 antagonist (CP-154,526) and a selective CRF2 antagonist (anti-sauvagine-30) (p>0.3, Student’s t-test). (B) 80% of the CRF-treated animals developed a partner preference in the absence of antagonist, while less than half of those received CRF1 or CRF2 antagonist developed a partner preference.