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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1923 Jun 30;38(1):73–79. doi: 10.1084/jem.38.1.73

THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS

M Heidelberger 1, O T Avery 1
PMCID: PMC2128423  PMID: 19868772

Abstract

1. A method is given for the concentration and purification of the soluble specific substance of the pneumococcus. 2. The material obtained by this method is shown to consist mainly of a carbohydrate which appears to be a polysaccharide built up of glucose molecules. 3. Whether the soluble specific substance is actually the polysaccharide, or occurs merely associated with it, is still undecided, although the evidence points in the direction of the former possibility.

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Selected References

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  1. Dochez A. R., Avery O. T. THE ELABORATION OF SPECIFIC SOLUBLE SUBSTANCE BY PNEUMOCOCCUS DURING GROWTH. J Exp Med. 1917 Oct 1;26(4):477–493. doi: 10.1084/jem.26.4.477. [DOI] [PMC free article] [PubMed] [Google Scholar]
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