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Adenovirus-mediated expression of GIRK currents in hippocampal neurons. Cells cultured for 5 d were coinfected with AdGIRK1+2 or AdGIRK1+4 and analyzed 2 d postinfection in 25 mM [K+]o and 250 nM tetrodotoxin. Currents in the presence (b) and absence (a) of 100 μM baclofen; 0.5 mM Ba2+ blocked basal and baclofen-activated GIRK currents (c).
