Table 2.
Characteristic | Meta-analyses (n=124) |
---|---|
Financial ties with one drug company | 49 (40) |
Mean (range), median quality score* | 6.66 (0-17), 7 |
Published in journal supplement | 21 (17) |
Searched or included non-English literature | 11 (9) |
Described process of data abstraction | 27 (22) |
Included non-randomised controlled trials | 38 (31) |
Included unpublished studies | 5 (4) |
Included studies that used only placebo group as control group | 27 (22) |
Focused on newer class of drug | 51 (41) |
Used surrogate outcomes only | 51 (41) |
Used composite outcomes only | 3 (2) |
Carried out evaluations of heterogeneity | 62 (50) |
Carried out sensitivity analyses | 70 (56) |
*Score was continuous variable from 0-18, with higher scores indicating better quality and lower scores indicating worse quality.