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Preconditioning inhibits late and dramatic mitochondrial membrane depolarization and cell death in PDK1fl/+, but not PDK1fl/−, mice. A) Original images of preconditioned PDK1fl/+ and PDK1fl/− cardiomyocytes loaded with JC-1 exposed to hypoxia. Horizontal white bar represents 30 μm. B) Time course corresponding to (A).
