TABLE 2.
Individual Characteristics of Olmsted County, Minnesota, Residents With Type 1 Diabetes Mellitus and Celiac Disease*
| Patient No./age (y)/sex | Age at diabetes diagnosis (y) | Age at CD diagnosis (y) | Gastrointestinal symptoms | EMA | tTg (U/mL) | Positive biopsy results† | HbAlc‡ | BMI (kg/m2) |
|---|---|---|---|---|---|---|---|---|
| 1/10/F | 7 | 10 | No | 1:5120 | 169.0 | Yes | 7.3±0.3 | 15 |
| 2/14/F | 10 | 10 | Yes | 1:320 | 89.6 | Yes | 6.2±0.6 | 25 |
| 3/17/M | 10 | 17 | No | 1:80 | 32.0 | Yes | 8.3±1.0 | 22 |
| 4/29/F | 10 | 29 | No§ | 1:5120 | 48.0 | Yes | 6.6±0.4 | 28 |
| 5/34/F | 16 | 28 | No | 1:640 | 59:3 | Yes | … | 27 |
| 6/45/M | 14 | 45 | No | 1:20 | 19:7 | Yes | 8.0±0.3 | 28 |
| 7/56/F | 22 | 56 | Yes | 1:640 | 139.7 | Yes | 7.8±0.4 | 23 |
| 8/31/F | 3 | 4 | Yes | … | … | Yes | … | 15 |
| 9/40/F | 9 | 11 | Yes | … | … | Yes | … | 17 |
| 10/65/F | 13 | 41 | Yes | … | … | Yes | … | 20 |
| 11/68/F | 12 | 59 | Yes | … | … | Yes | … | 22 |
*
Patients identified by serologic screening are indicated in bold-face type. BMI = body mass index (a measure of weight in kilograms divided by the square of height in meters); CD = celiac disease; EMA = endomysial antibody; HbAlc = hemoglobin Alc; tTg = tissue transglutaminase.
†
Biopsy positive refers to histologic features of CD observed on biopsy.
‡
Mean value 6 months before diagnosis of CD.
§
Developed biopsy-confirmed dermatitis herpetiformis. Cases 8 through 11 were clinically discovered with use of small bowel biopsy as the primary means of diagnosis and are included for completeness.