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. Author manuscript; available in PMC: 2008 Nov 1.
Published in final edited form as: Dev Biol. 2007 Aug 9;311(1):25–39. doi: 10.1016/j.ydbio.2007.08.003

Fig. 7. Ras signaling affects adherens junction morphology.

Fig. 7

The apGalts system was used to express GFP (A,B), RasV12 (C,D), or TkvQ235D (E,F) from 0–36 hours APF. Sections though 36 hour APF pupal wings imaged by TEM are shown. B,D,F are high magnification views of the apical, dorsal cell surface. (A) Arrows point to basal adhesion junctions between the dorsal and ventral wing epithelia. Arrowheads indicate the apical surfaces. (B) Arrowheads indicate adherens junctions between intervein cells. (C,D) RasV12 expression causes apico-basal extension of dorsal epithelial cells, wing blistering and enlarged apical adherens junctions (arrowheads D). (E,F) In contrast, TkvQ235D expression does not affect apical adherens junction morphology (arrowheads F). Vein lumen (vl), dorsal (d), ventral (v), haemocyte (h).