Figure 6. Correlation between NKp30L and NKp44L expression and NKp30 and NKp44-mediated lysis by NK cells.

(A) EM-3 and SD-1 cells were used as targets in a 4 h ⁵¹Cr release assay using IL2-activated NK cells from two different donors (NK1 and NK2) as effector cells at the indicated effector to target (E/T) ratios. (B) ⁵¹Cr release assay of EM-3 and SD-1 target cells in the presence of control antibodies (cIgG1) or blocking anti-NKp30 antibodies (αNKp30). (C–E) Lysis of K562 (C), HeLa (D) and Shep (E) cells by IL-2 activated NK cells in the presence of control antibodies (cIgG1) or blocking anti-NKp30 (αNKp30) and/or anti-NKp44 antibodies (αNKp44).