Abstract
Two tests are described for detecting antibody to the type-specific opacity factor (OF) of group A streptococci. This antibody was detected among patients convalescent from streptococcal sore throat in two communities in which outbreaks due to opacity factor-producing strains of group A streptococci occurred.
In an outbreak due to streptococci of M-type 22 there was a close correspondence between the distribution of anti-OF and of bactericidal M-antibody for the type. In a smaller outbreak due to M-type 58 streptococci, however, M-antibody was detected more often than antibody to OF.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- GOODER H. Association of a serum opacity reaction with serological type in Streptococcus pyogenes. J Gen Microbiol. 1961 Jul;25:347–352. doi: 10.1099/00221287-25-3-347. [DOI] [PubMed] [Google Scholar]
- KRUMWIEDE E. Studies on a lipoproteinase of group A streptococci. J Exp Med. 1954 Dec 1;100(6):629–639. doi: 10.1084/jem.100.6.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LANCEFIELD R. C. Persistence of type-specific antibodies in man following infection with group A streptococci. J Exp Med. 1959 Aug 1;110(2):271–292. doi: 10.1084/jem.110.2.271. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Top F. H., Jr, Wannamaker L. W. The serum opacity reaction of Streptococcus pyogenes. The demonstration of multiple, strain-specific lipoproteinase antigens. J Exp Med. 1968 May 1;127(5):1013–1034. doi: 10.1084/jem.127.5.1013. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WILLIAMS R. E. Laboratory diagnosis of streptococcal infections. Bull World Health Organ. 1958;19(1):153–176. [PMC free article] [PubMed] [Google Scholar]
- Wannamaker L. W. Differences between streptococcal infections of the throat and of the skin. I. N Engl J Med. 1970 Jan 1;282(1):23–31. doi: 10.1056/NEJM197001012820106. [DOI] [PubMed] [Google Scholar]
- Widdowson J. P., Maxted W. R., Grant D. L., Pinney A. M. The relationship between M-antigen and opacity factor in group A streptococci. J Gen Microbiol. 1971 Jan;65(1):69–80. doi: 10.1099/00221287-65-1-69. [DOI] [PubMed] [Google Scholar]
- Widdowson J. P., Maxted W. R., Grant D. L. The production of opacity in serum by group A streptococci and its relationship withthe presence of M antigen. J Gen Microbiol. 1970 Jun;61(3):343–353. doi: 10.1099/00221287-61-3-343. [DOI] [PubMed] [Google Scholar]