Skip to main content
NCBI home page
The Journal of Hygiene logoLink to The Journal of Hygiene
. 1970 Mar;68(1):101–110. doi: 10.1017/s0022172400028552

A comparative study of two live measles vaccines in Iran

H Mirchamsy, A Shafyi, Y Bassali, S Bahrami, F Nazari
PMCID: PMC2130774  PMID: 5266577

Abstract

The results of immunization of 523 children from 9 months to over 5 years of age with two attenuated measles vaccines, `Denken' and `Biken', are described. The clinical reactions following vaccination with both vaccines were mild, but Denken vaccine produced more rashes than the Biken vaccine. The serological conversion was satisfactory for both vaccines but a higher titre of neutralizing and haemagglutination-inhibiting antibodies was found in children immunized with Denken vaccine. The incidence of severe reactions or complications was negligible in this trial. The immunity to diphtheria or tetanus was not altered by vaccination with live measles vaccine.

Full text

PDF
101

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ENDERS J. F., KATZ S. L., MILOVANOVIC M. V., HOLLOWAY A. Studies on an attenuated measles-virus vaccine. I. Development and preparations of the vaccine: technics for assay of effects of vaccination. N Engl J Med. 1960 Jul 28;263:153–159. doi: 10.1056/NEJM196007282630401. [DOI] [PubMed] [Google Scholar]
  2. FADEEVA L. L., DADASHYAN M. A., LEBEDEV D. D., ZHDANOV V. M. Attenuated measles-virus strain in the U.S.S.R. Am J Dis Child. 1962 Mar;103:379–381. doi: 10.1001/archpedi.1962.02080020391039. [DOI] [PubMed] [Google Scholar]
  3. KUNITA N., KITAWAKI T., FUNAHASHI S., TOYOSHIMA K. COMPARISON OF THE HEMAGGLUTINATION INHIBITION TEST FOR MEASLES WITH SEROLOGICAL TESTS AND ITS APPLICATION TO A FIELD TRIAL. Biken J. 1963 Jul;6:45–56. [PubMed] [Google Scholar]
  4. MATUMOTO M., MUTAI M., SABURI Y., FUJII R., MINAMITANI M., NAKAMURA K. Live measles-virus vaccine: clinical trial of vaccine prepared from a variant of the Sugiyama strain adapted to bovine kidney cells. Jpn J Exp Med. 1962 Oct;32:433–448. [PubMed] [Google Scholar]
  5. Mirchamsy H., Nazari F., Stellman C., Esterabady H. The use of dried whole blood absorbed on filter-paper for the evaluation of diphtheria and tetanus antitoxins in mass surveys. Bull World Health Organ. 1968;38(4):665–671. [PMC free article] [PubMed] [Google Scholar]
  6. Mirchamsy H., Rapp F. Role of interferon in replication of virulent and attenuated strains of measles virus. J Gen Virol. 1969 Jun;4(4):513–522. doi: 10.1099/0022-1317-4-4-513. [DOI] [PubMed] [Google Scholar]
  7. Naficy K., Saidi S., Nategh R., Mostatab A., Akbarshahy E. Comparative study of live attenuated and further attenuated measles vaccines in rural areas of Iran. Arch Gesamte Virusforsch. 1967;22(1):11–22. doi: 10.1007/BF01240497. [DOI] [PubMed] [Google Scholar]
  8. Parisius W., Macmorine H. G. Effects of Tween 80 and freon 113 on measles virus. Appl Microbiol. 1969 Mar;17(3):379–383. doi: 10.1128/am.17.3.379-383.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. ROSEN L. Hemagglutination and hemagglutination-inhibition with measles virus. Virology. 1961 Jan;13:139–141. doi: 10.1016/0042-6822(61)90042-3. [DOI] [PubMed] [Google Scholar]
  10. SMORODINTSEV A. A., BOICHUK L. M., SHIKINA E. S., BATANOVA T. B., BYSTRYAKOVA L. V., PERADZE T. V. Clinical and immunological response to live tissue culture vaccine against measles. Acta Virol. 1960 Jul;4:201–204. [PubMed] [Google Scholar]
  11. Ueda S., Hosai H., Minekawa Y., Okuno Y. Studies on the combined use of killed and live measles vaccines. 3. Conditions for the "take" of live vaccine. Biken J. 1966 Jun;9(2):97–101. [PubMed] [Google Scholar]

Articles from The Journal of Hygiene are provided here courtesy of Cambridge University Press

RESOURCES