. Author manuscript; available in PMC: 2007 Dec 11.

Published in final edited form as: J Infect Dis. 2007 Feb 5;195(6):879–887. doi: 10.1086/511822

Table 3.

T cell immunophenotypes in peripheral blood from patients with secondary syphilis and healthy control subjects.

Surface antigens	Healthy control subjects (n = 5)	Patients with secondary syphilis
CD69/CD45RO		(n = 9)
CD4⁺CD69⁺CD45RO⁻	0.1 (0.08–0.3)	0.2 (0.1–1.3)
CD4⁺CD69⁺CD45RO⁺	0.2 (0.2–0.7)	0.9 (0.6–3.3)^a
CD4⁺CD69⁻CD45RO⁺	37.4 (31.3–50.6)	53.7 (49.5–71.1)^a
CD4⁺CD69⁻CD45RO⁻	62.3 (48.7–68.2)	39.5 (22.3–49.8)^a
CD8⁺CD69⁺CD45RO⁻	0.7 (0.4–1.4)	1.1 (0.8–2.2)
CD8⁺CD69⁺CD45RO⁺	2.4 (1.5–2.5)	2.3 (1.4–5.8)
CD8⁺CD69⁻CD45RO⁺	36.7 (34.5–49.4)	35.8 (28.7–55.5)
CD8⁺CD69⁻CD45RO⁻	59.2 (47.2–63.4)	60.5 (35.2–66.8)
HLA-DR/CD38		(n = 12)
CD4⁺CD38⁻HLA-DR⁺	1.3 (0.9–2.0)	1.3 (0.8–2.4)
CD4⁺CD38⁺HLA-DR⁺	0.5 (0.3–2.7)	1.9 (1.6–3.2)
CD4⁺CD38⁺HLA-DR⁻	3.8 (2.6–5.6)	15.4 (9.1–27.0)^a
CD4⁺CD38⁻HLA-DR⁻	94.2 (89.9–96.1)	77.6 (67.0–88.1)^a
CD8⁺CD38⁻HLA-DR⁺	0.3 (0.2–1.9)	2.6 (0.5–5.0)
CD8⁺CD38⁺HLA-DR⁺	0.5 (0.4–8.9)	2.1 (0.8–3.8)
CD8⁺CD38⁺HLA-DR⁻	3.5 (1.7–13.9)	9.2 (4.9–27.8)
CD8⁺CD38⁻HLA-DR⁻	95.6 (75.5–98.0)	80.8 (60.1–91.0)

NOTE. Data are median percentage (25th–75th percentile).

P < .05, patients with secondary syphilis vs. healthy control subjects (Mann-Whitney U test).