Table 2.
Laboratory-based evaluations of safety
| Test | Glucosamine Wk. 0 | Glucosamine Wk. 8 | Reparagen Wk. 0 | Reparagen Wk. 8 |
| Neutrophils % | 63.46 ± 1.25 | 63.54 ± 1.26 | 62.19 ± 1.32 | 62.38 ± 1.27 |
| Lymphocytes % | 31.73 ± 1.21 | 32.00 ± 1.27 | 32.27 ± 1.18 | 32.27 ± 1.21 |
| Monocytes % | 1.17 ± 0.14 | 1.32 ± 0.15 | 1.11 ± 0.13 | 1.16 ± 0.15 |
| Eosinophils % | 3.54 ± 0.36 | 3.22 ± 0.30 | 4.11 ± 0.47 | 3.19 ± 0.41 |
| Basophils % | 0.02 ± 0.02 | 0 ± 0 | 0 ± 0 | 0 ± 0 |
| White blood cells mm3 | 7929 ± 268 | 7515 ± 222 | 7753 ± 303 | 7496 ± 262 |
| Red Blood Cells mm3 | 4.06 ± 0.10 | 4.04 ± 0.08 | 4.13 ± 0.11 | 4.15 ± 0.08 |
| Hemoglobin gm/dl | 12.02 ± 0.3 | 12.00 ± 0.2 | 11.84 ± 0.3 | 11.92 ± 0.2 |
| Erythrocyte Sedimentation Rate mm | 33.0 ± 3.6 | 30.3 ± 3.0 | 33.9 ± 3.4 | 28.5 ± 3.1a |
| SGPT IU/L | 26.3 ± 2.6 | 23.6 ± 1.7 | 22.9 ± 2.1 | 19.9 ± 1.3 |
| Creatinine mg/dl | 0.97 ± 0.03 | 0.93 ± 0.03 | 1.17 ± 0.21 | 0.93 ± 0.03 |
Data expressed as a mean ± SEM.
There was no difference between baseline and week 8 values for the treatment groups with the exception of erythrocyte sedimentation rate as denoted by the letter a (p < 0.05). As the analysis was done on a paired basis completion of the protocol was necessary, hence the analysis is per protocol, glucosamine n = 41, reparagen n = 38.