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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1930 May 31;51(6):965–976. doi: 10.1084/jem.51.6.965

INFECTIOUS MYXOMATOSIS OF RABBITS

OBSERVATIONS ON THE PATHOLOGICAL CHANGES INDUCED BY VIRUS MYXOMATOSUM (SANARELLI)

T M Rivers 1
PMCID: PMC2131848  PMID: 19869741

Abstract

The virus of infectious myxomatosis of rabbits (Sanarelli) induces multiple lesions in the skin, lymph glands, tunica vaginalis,epididymis, testicle, spleen, and lungs. Growth and destruction of cells in the epidermis overlying the myxomatous masses leads to the formation of vesicles. Cytoplasmic inclusions are found in affected epidermal cells. Occasionally, similar inclusions are seen in other involved epithelial cells. The nature of the inclusions is an open question. In the myxomatous masses situated in the subcutaneous and other tissues, evidences of alteration and growth of certain cells are observed.

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Selected References

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  1. Rivers T. M. Some General Aspects of Pathological Conditions Caused by Filterable Viruses. Am J Pathol. 1928 Mar;4(2):91–124.15. [PMC free article] [PubMed] [Google Scholar]

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