Abstract
The Reynals factor promotes the pathogenic action of the viruses of herpes, vesicular stomatitis of horses, Borna disease, and vaccinia. The heightening of virulence is revealed in various ways. The effects of the viruses may be accentuated; or a weak strain converted into a strong one, as in the case of the F. strain of herpes virus; or the power acquired to infect resistant species or tissues, as, e.g., rabbits and the abdominal skin of guinea pigs, with acute vesicular stomatitis. The Reynals factor should serve as an important agent in the study of filterable viruses.
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Selected References
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- Duran-Reynals F. THE EFFECT OF EXTRACTS OF CERTAIN ORGANS FROM NORMAL AND IMMUNIZED ANIMALS ON THE INFECTING POWER OF VACCINE VIRUS. J Exp Med. 1929 Aug 31;50(3):327–340. doi: 10.1084/jem.50.3.327. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Flexner S., Amoss H. L. CONTRIBUTIONS TO THE PATHOLOGY OF EXPERIMENTAL VIRUS ENCEPHALITIS : III. VARIETIES AND PROPERTIES OF THE HERPES VIRUS. J Exp Med. 1925 Feb 28;41(3):357–377. doi: 10.1084/jem.41.3.357. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Olitsky P. K. PHYSICAL, CHEMICAL, AND BIOLOGICAL STUDIES ON THE VIRUS OF VESICULAR STOMATITIS OF HORSES : COMPARISON WITH THE VIRUS OF FOOT-AND-MOUTH DISEASE. J Exp Med. 1927 May 31;45(6):969–981. doi: 10.1084/jem.45.6.969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pijoan M. THE ACTION OF TESTICLE, KIDNEY, AND SPLEEN EXTRACTS ON THE INFECTIVE POWER OF BACTERIA. J Exp Med. 1931 Jan 1;53(1):37–42. doi: 10.1084/jem.53.1.37. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stewart F. W., Duran-Reynals F. A STUDY OF THE GENERALIZATION OF VACCINE VIRUS FROM ENHANCED SKIN LESIONS. J Exp Med. 1929 Aug 31;50(3):341–353. doi: 10.1084/jem.50.3.341. [DOI] [PMC free article] [PubMed] [Google Scholar]