TABLE I.

MEAN PhIP-DNA ADDUCT LEVELS IN PROSTATE TUMOR CELLS EXPRESSED AS ABSORBANCE UNITS FOR ALL SUBJECTS AND STRATIFIED BY RACE

	All subjects (n = 264)			Caucasians (n = 162)			African–Americans (n = 102)
	n	Mean ± SE	p value	n	Mean ± SE	p value	n	Mean ± SE	p value
Age at prostatectomy
<60	114	0.105 ± 0.003	0.91	66	0.105 ± 0.003	0.36	48	0.103 ± 0.004	0.34
60+	150	0.104 ± 0.002		96	0.102 ± 0.003		54	0.109 ± 0.004
PSA at diagnosis
Low (<4 ng/mL)	45	0.105 ± 0.004	0.88	34	0.106 ± 0.004	0.38	11	0.104 ± 0.008	0.53
Moderate (4–10 ng/mL)	176	0.105 ± 0.002		98	0.104 ± 0.003		78	0.105 ± 0.003
High (>10 ng/mL)	43	0.103 ± 0.004		30	0.097 ± 0.005		13	0.114 ± 0.008
Tumor volume
Low (<20% of gland)	136	0.110 ± 0.002	0.0006	82	0.109 ± 0.003	0.003	54	0.111 ± 0.004	0.07
High (≥20% of gland)	128	0.099 ± 0.002		80	0.097 ± 0.003		48	0.101 ± 0.004
Prostate volume
Low (< 65 cc)	133	0.108 ± 0.002	0.02	78	0.105 ± 0.003	0.35	55	0.112 ± 0.004	0.02
High (≥65 cc)	131	0.101 ± 0.002		84	0.101 ± 0.003		47	0.099 ± 0.004
Tumor stage
2	204	0.105 ± 0.002	0.54	125	0.103 ± 0.003	0.76	79	0.107 ± 0.003	0.56
3 or 4	60	0.103 ± 0.003		37	0.102 ± 0.004		23	0.103 ± 0.004
Advanced Gleason Grade1
No	200	0.103 ± 0.002	0.31	122	0.103 ± 0.002	0.97	78	0.104 ± 0.004	0.10
Yes	64	0.107 ± 0.003		40	0.103 ± 0.004		24	0.114 ± 0.006

¹No = Gleason sum 6 or less or Gleason sum 7 and primary Gleason grade 3 or lower; Yes = Gleason sum 8 or higher or Gleason sum 7 and primary Gleason grade 4 or higher.