TABLE II.

MEAN PhIP-DNA ADDUCT LEVELS IN PROSTATE NON-TUMOR CELLS EXPRESSED AS ABSORBANCE UNITS FOR ALL SUBJECTS AND STRATIFIED BY RACE

	All subjects (n = 264)			Caucasians (n = 162)			African–Americans (n = 102)
	n	Mean ± SE	p value	n	Mean ± SE	p value	n	Mean ± SE	p value
Age at prostatectomy
<60	114	0.167 ± 0.004	0.99	66	0.169 ± 0.005	0.53	48	0.164 ± 0.007	0.47
60+	150	0.167 ± 0.004		96	0.165 ± 0.004		54	0.171 ± 0.006
PSA at diagnosis
Low (<4 ng/mL)	45	0.105 ± 0.004	0.88	34	0.161 ± 0.007	0.56	11	0.153 ± 0.014	0.37
Moderate (4–10 ng/mL)	176	0.105 ± 0.002		98	0.170 ± 0.004		78	0.168 ± 0.005
High (>10 ng/mL)	43	0.103 ± 0.004		30	0.162 ± 0.008		13	0.179 ± 0.013
Tumor Volume
Low (<20% of gland)	136	0.173 ± 0.004	0.02	82	0.175 ± 0.005	0.02	54	0.171 ± 0.006	0.52
High (≥20% of gland)	128	0.161 ± 0.004		80	0.159 ± 0.005		48	0.165 ± 0.007
Prostate volume
Low (<65 cc)	133	0.171 ± 0.004	0.11	78	0.172 ± 0.005	0.11	55	0.170 ± 0.006	0.59
High (≥65 cc)	131	0.163 ± 0.004		84	0.161 ± 0.005		47	0.165 ± 0.007
Tumor stage
2	204	0.166 ± 0.003	0.65	125	0.167 ± 0.004	0.81	79	0.166 ± 0.005	0.31
3 or 4	60	0.169 ± 0.006		37	0.165 ± 0.007		23	0.177 ± 0.010
Advanced Gleason Grade1
No	200	0.165 ± 0.003	0.09	122	0.167 ± 0.004	0.94	78	0.161 ± 0.005	0.005
Yes	64	0.175 ± 0.005		40	0.166 ± 0.007		24	0.190 ± 0.009

¹No = Gleason sum 6 or less or Gleason sum 7 and primary Gleason grade 3 or lower; Yes 5 Gleason sum 8 or higher or Gleason sum 7 and primary Gleason grade 4 or higher.