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. 1997 Mar 10;136(5):1047–1058. doi: 10.1083/jcb.136.5.1047

Table I.

Inhibition of Agrin–induced Clustering by a Tyrphostin

Treatment Cells with more than five AChR-containing clusters Inhibition
No inhibitor 100 μM RG50864
None 0.6 ± 0.2%
(five cultures)
6 nM Laminin 1.9 ± 1.1%
(four cultures)
1/200 Agrin 96% 57% 40.6%
1/200 Agrin 94% 21% 77.7%
1/1000 Agrin 55%  8% 85.5%

The treatments with laminin and agrin were for 1 d. At least 100 muscle cells were assessed in each culture. All AChR-containing clusters were counted, independent of their size.  

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